Tag Archives: dna synthesis
Anemia, Megaloblastic (Vitamin B12 and Folic Acid Deficiency)

Anemia, Megaloblastic (Vitamin B12 and Folic Acid Deficiency)

The anemias caused by deficiencies of the vitamins B12 and folic acid show identical bone marrow and peripheral blood changes. Both vitamins are essential for DNA synthesis. Pathophysiology The two main vitamin deficiencies may coexist. In each case, hyperplasia of the bone marrow occurs, and the precursor erythroid and myeloid cells are large and bizarre […]

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Anti-infective Agents

Anti-infective Agents

Anti-infective Agents Drug Therapy Across the Lifespan Development of Anti-infective Therapy 1920s Paul Ehrlich worked on developing a synthetic chemical effective against infection-causing cells only Scientists discovered penicillin in a mold sample 1935 The sulfonamides were introduced Mechanisms of Action Interfere with biosynthesis of the bacterial cell wall Prevent the cells of the invading organism […]

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